In an effort to examine the silencing efficiency of EGFR and Galectin-1 in U87 human GBM line, CS lipid nanocapsules were complexed with anti-EGFR and anti-galactin-1 small interfering RNA (siRNA) and administered via convection enhanced delivery (CED) (a minimally invasive surgery that placed catheters directly into the tumor bed to deliver pharmaceutical agents) in athymic nude mice (60). Here, EGFR is linked to neoplasm.