While P50 has a strong link to the CHRNA7 gene and the GABAB receptor (116, 117, 152), the evidence for P50 as an endophenotype of schizophrenia is inconsistent for heritability, test-retest reliability, and heritability (24, 39, 58, 89, 120, 122, 133, 134, 139, 170) suggesting that more studies are required to ascertain if P50 can be used as an endophenotype in schizophrenia. Here, CHRNA7 is linked to schizophrenia.