C6 and Hepatic fibrosis: Among the 29 genes, complement component 6 (C6) and lipopolysaccharide binding protein (LBP) are involved in innate immunity while ephrin type-B receptor 2 (EPHB2) and annexin A2 (ANXA2) are associated with hepatic fibrosis (Kolgelier et al., 2015; Mimche et al., 2015; Zhou et al., 2016).