Indeed, Que (25 μM) was added to the cell cultures and it reduced the accumulation fatty acids and their metabolites in human Simpson Golabi Behmel Syndrome (SGBS) preadipocytes, probably through the Enolase 2 gene that is vital for the conversion 2-phosphoglycerate into phosphoenolpyruvate (Leiherer et al., 2016). Here, ENO2 is linked to Simpson-Golabi-Behmel syndrome.