In addition, mesenchyme homeobox 1 (Meox1), placental growth factor (pgf) and insulin-like growth factor binding protein 4 and 5 (Igfpb4 and 5) were among the genes associated with angiogenesis and upregulated following stroke (Freitas-Andrade et al., 2012; Smith et al., 2018; Wu et al., 2018; Munji et al., 2019). The gene discussed is PGF; the disease is stroke disorder.