A genetic variant (rs1872328) in Acylphosphatase 2 (ACYP2), coding for a protein thought to be responsible for hair cell development, was found to be significantly associated with hearing loss in pediatric patients treated with cisplatin for embryonal tumors (Xu et al., 2015) and osteosarcomas (Vos et al., 2016). The gene discussed is ACYP2; the disease is embryonal neoplasm.