Chemokines also take part in the pathogenesis of hypertension, including monocyte chemoattractant protein-1 (MCP-1, CCL2), Gro-α (growth-related oncogene), interferon-inducible protein (IP-10, CXCL10) interleukin-8 (IL-8; CXCL8), CXCL1/RaNTeS (CCL5)/CCR5 and fractalkine (FKN aka CX3CL1)/CX3CR1 (Martynowicz et al., 2014). This evidence concerns the gene CXCL10 and hypertensive disorder.