Furthermore, we revealed that β5i is involved in the modulation of the infiltration of proinflammatory cells into abdominal aortic aneurysm and atherosclerotic lesion, as well as vascular remodeling in ApoE knockout mice (Li F. D. et al., 2019; Wang et al., 2020). The gene discussed is APOE; the disease is abdominal aortic aneurysm.