According to the expert consensus on the diagnosis and treatment of anemia caused by renal failure (2014) and the expert consensus on the rational use of Recombinant Human Erythropoietin in anemia caused by renal failure (2007), the timing of medication for anemia caused by renal failure and anemia caused by chemotherapy for non-bone marrow malignant tumors should be Hb≤ 120g/L. The gene discussed is GSTM1; the disease is Renal insufficiency.