When Hb reaches 140g/L (Garrido-Martín et al., 2012) and 150g/L (Colomina et al., 2004) in the process of using rhEPO, rhEPO should be stopped in time, and blood coagulation indexes should be closely monitored to prevent the occurrence of various forms of thromboembolism. This evidence concerns the gene GSTM1 and Thromboembolism.