NFKB1 and cystic fibrosis: Consequently, these results have led to the proposal that upregulated inflammation is related to the molecular defect of CF with a strong implication of nuclear factor kappa B (NFκB) or mitogen-activated protein (MAP) kinase pathways with other transcription factors including NFAT, NF-IL6, AP1 and AP2 (Tabary et al., 1999; Tabary et al., 2003; Muselet-Charlier et al., 2007).