Similar to the etiopathogenesis of retinopathy of prematurity (ROP), induction of hypoxia-inducible factor-1 α (HIF-1α) may be responsible for the production of vascular endothelial growth factor (VEGFA), which is the main cause of retinal neovascularization (Aiello et al., 1994; Arjamaa and Nikinmaa, 2006; Abu El-Asrar et al., 2012). Here, HIF1A is linked to retinopathy of prematurity.