NFKBIA and inflammatory bowel disease: Such a complex promotes phosphorylation and degradation of IκB-α (Inhibitor kappa B-alpha), resulting in the dissociation and release of NF-κB p65, known as an important factor in regulating this highly expressed immune process in patients with IBD (Trzeciak-Jędrzejczyk et al., 2017; Yao et al., 2017; Lu et al., 2018).