We did not observe any association between CYP2D6 polymorphism and the PANSS percent change in our sample of 130 Asian patients with schizophrenia (t=0.561, p=0.576 at 2 weeks; t=0.196, p=0.845 at 4 weeks; t=-0.129, p=0.898 at six weeks). Here, CYP2D6 is linked to schizophrenia.