In addition, our molecular data indicate that, in a dyskinetic PD rat model, rapamycin administration prevented the activation of striatal mTORC1 signaling without influencing the overactivation of PKA/DARPP-32 and pERK pathways, as well as the total protein expression of AMPA and NMDA receptor subunits. The gene discussed is PPP1R1B; the disease is Parkinson disease.