SOD1 and Parkinson disease: Increased oxidative stress and decreased antioxidant capacity including reduced SOD and increased 4-HNE are among pathological findings in postmortem brains of human PD and the MPTP-induced PD mouse model (Yoritaka et al., 1996; Castellani et al., 2002; Sofic et al., 2006; Li and Pu, 2011; Lv et al., 2012).