Moreover, PD-associated proteins including LRRK2 (Orenstein et al., 2013; Manzoni et al., 2016), PINK1 (Lazarou et al., 2015), PRKN (Narendra et al., 2008) and ATP13A2 (ATPase cation transporting 13A2; Bento et al., 2016) are involved in autophagy-processing modulation as well. Here, LRRK2 is linked to Parkinson disease.