NFKB1 and Parkinson disease: The roles of ginkgolides in IIR are also supported by the study of Kim et al., wherein they found that GB can significantly attenuate the increase of the NF-κB DNA-binding activity induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (can induce PD rodent model through an NF-κB-dependent mechanism; Kim et al., 2013).