MMP9 and Huntington disease: The pro-inflammatory cytokines IL-6, TGF-β1 as well as vascular growth factor (VEGF), matrix metallopeptidase 9 (MMP-9) and chemokines eotaxin-3, MIP-1β, MCP-1 and MCP-4 have also been reported to be increased in HD patients (Dalrymple et al., 2007; Chang et al., 2015; Connolly et al., 2016).