Encoding glycyl-tRNA synthetase (GlyRS), which charges glycine, GARS1 is the first and best-studied ARS gene linked to CMT (designated CMT type 2D, CMT2D, OMIM: 601472; Antonellis et al., 2003). The gene discussed is GARS1; the disease is Charcot-Marie-Tooth disease type 2D.