GARS1 and Autosomal dominant Charcot-Marie-Tooth disease type 2D: We also assessed L1-L5 DRG of 1-month-old GarsNmf249/+ mice and saw the same pattern of enhanced GlyRS fluorescence in a subset of DRG neurons (Figure 5E), thus indicating that the increase of mutant GlyRS levels in L1-L5 DRG is an early event in CMT2D pathogenesis.