HGF and Intraventricular hemorrhage: Our previous study also found that Bdnf and hepatocyte growth factor increased significantly in the serum, cerebrospinal fluid, and brain tissue of mice after intravenous administration of UC-MSCs in a neonatal intraventricular hemorrhage model and that periventricular reactive gliosis, hypomyelination, and periventricular cell death observed after IVH were significantly attenuated (Mukai et al., 2017).