PRKN and Parkinson disease: By now, the list of genes involved in PD pathogenesis includes genes responsible for autosomal dominant PD (such as PARK1/SNCA, LRRK2, VPS35, EIF4G1, DNAJC13, and CHCHD2), autosomal recessive PD (such as Parkin, PINK1 and DJ-1) or less typical parkinsonian syndromes (for instance, PLA2G6 or ATP13A2; Kalia and Lang, 2015).