Sinha et al. (2018) found that ABCA7 genetic risk differentially affects intra- MTL functional connectivity between MTL subfields, versus internetwork connectivity of the MTL with the MPFC, in non-demented older African Americans. Liao et al. (2014) found that ABCA7 rs3764650 was significantly associated with AD and the influence of ABCA7 was only evident in individuals without APOEε4 alleles in elderly subjects (Liao et al., 2014). Mcfall et al. (2016) found that the cumulative genetic risk of APOE plus CLU had relation to executive function performance in older adults. This evidence concerns the gene ABCA7 and Alzheimer disease.