It is thought that one or several mTBIs give rise to alterations in inflammatory processes in the brain via activation of astrocytes and microglial cells (Mouzon et al., 2014; Papa et al., 2015; Winston et al., 2016), as well as the more direct neuronal insults including axonal degeneration, neuronal cell loss (Daneshvar et al., 2015; McKee and Daneshvar, 2015), and intracranial accumulation of dementia-related damaging proteins including amyloid beta peptide (Aβ), and phosphorylated forms of Tau (p-Tau; Papa et al., 2015; Gill et al., 2018). Here, MAPT is linked to dementia.