To determine the in vivo contribution of fibroblast TXNDC5 to pulmonary fibrosis, we generated a mouse line with inducible, fibroblast-specific Txndc5 deletion (Col1a2-Cre/ERT2*Txndc5fl/fl, abbreviated as Txndc5cKO, Supplementary Fig. 11). The gene discussed is TXNDC5; the disease is pulmonary fibrosis.