MYD88 and B-cell chronic lymphocytic leukemia: In our study, although L265P mutation was associated with several favorable prognostic factors, we did not find a difference in TTFT among patients with wild type vs. mutated MYD88. Of note, evaluating prognosis in this scenario is challenging due to the low frequency of MYD88 mutations, the clinically indolent nature of CLL, and the presence of other confounding factors associated with prognosis.