Evidences indicate that increase of IL-6 was not only occurred in liver ablation, researches focus on lung cancer, including primary lung cancer and pulmonary metastases demonstrated that serum IL-8, IL-1β, IL-6, IL-10, IL-12 and TNF-α were significantly raised after radiofrequency thermal ablation [25]. The gene discussed is CXCL8; the disease is lung cancer.