Furthermore, IACS-010759 and venetoclax could cooperate in inhibiting AML cell proliferation, though its role in tumor growth inhibition would be minor since combined treatment of MV4-11 cells cultured in glucose supplemented media and THP-1 cells cultured in galactose supplemented media (both cell lines are OXPHOS-dependent under these experimental conditions) for 24 h resulted in 90% cell death, accompanied by significantly increased cytochrome c release. The gene discussed is CYCS; the disease is neoplasm.