For instance, Hemopurifier®, an affinity-based purifier developed by Aethlon Medical Inc. (San Diego, CA, USA), has been shown to selectively capture viral particles (which have similar size as sEVs) in the plasmas of individuals infected with Hepatitis C and Human Immunodeficiency Virus (HIV) [100,101], and this device is being modified and tested for removal of Her2-positive breast cancer exosomes from patient plasma ([64], https://grantome.com/grant/NIH/R43-CA232977-01). This evidence concerns the gene ERBB2 and breast cancer.