Although their neighbouring codriver genes in the 11q13 chromosomal band—CCND1 and CTTN—have been recently meta-analysed by our group [25,26], showing their promising utility as prognostic tools in HNSCC, there is not enough evidence on the prognostic significance of FADD upregulation in HNSCC. This evidence concerns the gene CTTN and head and neck squamous cell carcinoma.