Finally, to examine the relationship between lncRNA perturbators and lncRNA-perturbated mRNAs, we overexpressed lncRNA SNHG7 and TUG1 in the A549 lung adenocarcinoma cell line and experimentally validated their function to remarkably enhance the expression of PNMA2 and CDC7 respectively. Here, PNMA2 is linked to lung adenocarcinoma.