We found four paired lncRNA-mRNA exhibiting a substantially high SCNA frequency in cancers (Figure 2C,D), including lncRNA FGD5-AS1 and PRKAR2A (KIRC, 44.2% and 44.4%), lncRNA TUG1 and CDC7 (LUAD, 25.9% and 23.6%), lncRNA TUG1 and DSC2 (LUAD, 25.9% and 26.1%) and lncRNA SNHG7 and PNMA2 (LUAD, 25.4% and 31.1%). Here, DSC2 is linked to cancer.