EGFR and viral infectious disease: As can be seen in Figure 2A, sustained activation of EGFR was stimulated during virus infection in MDBK cells, with phospho-EGFR(Y1068) protein levels increased to approximately 3.8-, 7.6-, 8.9-, and 6.1-fold relative to the uninfected control at 4, 8, 12, and 24 hpi, respectively (Figure 2B).