Specifically, MIR199A2, MIR218-2, MIR24-2, MIR92A1, and MIR99A were upregulated in AD, while MIR129-2, MIR1296, MIR219A1, MIR29B1, MIR375, MIR411, and MIR431 were downregulated in AD. This evidence concerns the gene MIR431 and Alzheimer disease.