GSK3B and mood disorder: Over expression of LINC02151 in these mice upregulates phosphorylated-GSK3β (p-GSK3β) protein and β-catenin in the hippocampus suggesting the deficits in LINC02151 seen in humans may involve disruption of the Wnt/β-catenin pathway, which has previously been implicated in the molecular dysfunction of mood disorders [91].