BNP is an important indicator for predicting heart failure in patients with AMI.[36] TnT and hs-CRP can reflect the severity of myocardial necrosis and are related to the prognosis.[37] Seattle angina pectoris scale is used to evaluate the clinical symptoms and quality of life, Hospital Depression Anxiety Scale, and PSQI are used to reflect the internal mental state of patients. This evidence concerns the gene NPPB and Myocardial necrosis.