In Kaplan-Meier curves analysis for the NSCLC cohort, MUC16 mutation was significantly associated with prolonged OS (median, not reached vs 11.3 months; hazard ratio, 0.34; 95% CI, 0.12-0.99; P = .04, log-rank test) (Figure 3A). Here, MUC16 is linked to non-small cell lung carcinoma.