2.Non-steroidal anti-inflammatory drugs (NSAIDs): At the beginning of the spread of the SARS-CoV-2 infection, European doctors indicated the non-use of ibuprofen or another NSAID, due to the risk of increasing levels of angiotensin-converting enzyme (ACE); thus, worsening COVID-19 (12). The gene discussed is ACE; the disease is COVID-19.