EPSTI1 and myeloid sarcoma: In the top-list of genes with increased expression are several proteins that have shown to play a role in activation of the immune response in MS like EPSTI1 and IFI6.17,18 In the top-list of genes with reduced expression RPS6KA3 is of interest, as this gene has been shown to be downregulated in blood from MS patients in remission.19