We followed up the patients for 2 years, and the AID-positive DHL was worse than the AID-positive DLBCL OS, with a statistical difference (P = 0.025), (Fig. 1D), but there is no difference between AID-negative DHL and DLBCL (Fig. 1E). The gene discussed is AICDA; the disease is diffuse large B-cell lymphoma.