Although the definitive explanations for this observation remain uncertain and could be an area for future exploration, possible postulations include procalcitonin, unlike CRP, is a marker more specific for bacterial infection than for proinflammatory conditions in general and procalcitonin changes more rapidly than CRP does35 and thus CWA parameters might not parallel the fluctuations in procalcitonin well. Here, CRP is linked to bacterial infectious disease.