Chimæra analysis of CG118 profiles (Fig. 6b) suggested that the tumor was composed of primarily two types of cells: tumor subclones with a CTNNB1 (S45F) mutation and those with a mutation in WT1 (R445W) mutation; a predicted daughter clone of the CTNNB1 mutation had no previously studied mutations. Here, CTNNB1 is linked to neoplasm.