CSPG4 and experimental autoimmune encephalomyelitis: Previous studies observed NG2 immunoreactivity in a subset of activated Iba1+ microglia and/or macrophages (below referred to as microglia for simplicity) in a variety of disease models such as demyelination models induced by lysolecithin or experimental autoimmune encephalomyelitis (EAE) [3, 33, 40, 45], epilepsy model by kainate injection [6], neuroinflammation model by LPS injection [59, 62], or the acute injury models transient middle cerebral artery occlusion (tMCAO) and stab wound injury (SWI) [18, 38, 52, 60].