M. sexta genes up-regulated during infection and their homologs in all three mouse tissues include serine peptidase inhibitors (Serpinb3 c, Serpinb3b), a Ras-like protein (Rit2), transmembrane proteases (Tmprss11a, Tmprss11 f), a histidine decarboxylase (Hdc), and a peptidoglycan recognition protein (Pglyrp3). The gene discussed is PGLYRP1; the disease is infection.