SEMA3A and Recurrent tonsillitis: Only 3 of 17 (17.64%) chronic tonsillitis tissues showed low SEMA3A expression, whereas 19 of 32 (59.37%) specimens of OPC tissue displayed low SEMA3A expression, indicating that SEMA3A expression was significantly upregulated in the OPC tissues compared with chronic tonsillitis tissues (p = 0.005) (Table 1).