Surprisingly, we found that IL-1β did not activate the phosphorylation of JNK in HMC3 cells when compared with TOV21G, a human ovarian cancer cell line (used as a control for JNK phosphorylation), induced by 10% fetal bovine serum (FBS) for 30 min (Figure 4B). The gene discussed is IL1B; the disease is ovarian cancer.