In contrast, ApoA5 / ApoC3 modulation was predicted to lower PD risk, and estimated with higher precision (odds ratio (OR) per SD lower triglycerides from ApoA5 / ApoC3 modulation = 0.82; 95% CI = 0.72, 0.94; p = 0.005). This evidence concerns the gene APOC3 and Parkinson disease.