Hence, this lethal malnutrition‐like phenotype could have been a result of the combined lack of LAT4 in SI and kidney together with its defect in other organs and cell types, such as the endocrine pancreas, brain and leukocytes, and/or via indirect effects, in particular at the level of metabolically active organs such as the liver. The gene discussed is SLC43A2; the disease is nutritional deficiency disease.