Among AA in our MVP cohort, significant associations with NAFLD and/or ALT were detected for 6 variants, including PNPLA3 (rs738409) and PPP1R3B (rs4240624), which were previously reported in 3,124 AA patients examined for hepatic steatosis by CT [61]. This evidence concerns the gene PNPLA3 and metabolic dysfunction-associated steatotic liver disease.