At 900 mg (DL4), one patient developed a DLT (grade 4 hepatic enzymes increased); this 61-year-old female diagnosed with gastric adenocarcinoma and liver and peritoneum metastases had liver enzymes (AST/ALT) increased to 664 UI/L and 425 UI/L, respectively, 8 days after the first dose. This evidence concerns the gene GPT and gastric adenocarcinoma.