The only differentially expressed gene represented in the prediction model was DAB2. Interestingly, DAB2’s promoter is known to be methylated in oral carcinomas31, low DAB2 expression promotes esophageal squamous cell carcinoma tumor progression and poor prognosis32, and DAB2 is functionally linked to thrombin signaling and platelet activation in humans33. This evidence concerns the gene DAB2 and neoplasm.