GVL promotion by FGK45 was not due to a direct action on BC-CML cells as FGK45 did not reduce BC-CML numbers in RAG2−/−γc−/− mice transplanted with BC-CML cells and no T cells (Supplementary Fig. 2B). The gene discussed is RAG2; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.