Although the two groups did not differ significantly in age, gender, body mass index (BMI), hemoglobin, glycated hemoglobin (HBA1c), duration of type 2 diabetes mellitus (T2DM) and hypertension, patients in the high dp-ucMGP group had significantly lower serum albumin, higher proteinuria levels, and lower eGFR at baseline. The gene discussed is ALB; the disease is type 2 diabetes mellitus.